Madre de Dios Region Holidays

Book a Hotel + Flight or Car together to unlock savings

Photo by nevin xavier

  • Plan, book, travel with confidence

  • Better together

    Save up to AU$2,500 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Madre de Dios Region Holiday

Choose one of our holiday packages to Madre de Dios Region and wander wherever your adventurous soul takes you. Hiking and nature are just a couple of the things you can look forward to in this wonderful destination. Start your trip to Madre de Dios Region by spending a few nights in Tambopata, one of the top cities here. Expedia has hotels, flights and all your other travel needs to help you curate your very own customised Madre de Dios Region holiday today.

Our guide on where to stay in Madre de Dios Region

Find the best Madre de Dios Region areas for the activities you enjoy most.

Chapajal

While Chapajal isn't home to many top sights, Puerto Maldonado Plaza de Armas and Puerto Maldonado Obelisk are some notable places to visit nearby.

Madre de Dios Region Essential Information

Language
Spanish
Currency
Peruvian sols
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Padre Aldamiz Intl. Airport (PEM)
Top Sights
Tambopata National Reserve, Sandoval Lake and Manu National Park

Our pick of the best Madre de Dios Region Hotel Deals

IKAM Riverview Amazon Lodge - Asociado Casa Andina

IKAM Riverview Amazon Lodge - Asociado Casa Andina

3 out of 5
Tambopata KM. 7 Otr. Carretera Bajo Tambopata Madre de Dios
The price is AU$318 per night from 5 July to 6 July
AU$318
5 July - 6 July
9/10 Wonderful! (16 reviews)
"The lodge was superb, very helpful and friendly staff all round. They were very flexible with meals for our children (5 & 8 years). All staff I spoke to were really knowledgeable about the local plants and animals but special shout out to Yuri who led our multiple excursions. Only small suggestion ..."

Reviewed on 5 June 2026

IKAM Riverview Amazon Lodge - Asociado Casa Andina
Libelula Hotel

Libelula Hotel

2 out of 5
Jr Puno No. 429 Tambopata Madre de Dios
Fully refundableReserve now, pay when you stay
The price is AU$58 per night from 6 June to 7 June
AU$58
6 June - 7 June
9/10 Wonderful! (29 reviews)
"Good hotel! Recommend to book"

Reviewed on 14 May 2026

Libelula Hotel
Tambopata Research Center

Tambopata Research Center

3 out of 5
Tambopata River Inambari Madre De Dios
The price is AU$1,441 per night from 7 June to 8 June
AU$1,441
7 June - 8 June
Tambopata Research Center
See all 56 properties in Madre de Dios Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
All Inclusive Holidays
Cheap Holidays
Cheap Holidays
Cheap Holidays
beach holidays
Beach Holidays
Beach Holidays

Frequently asked questions

How much does a Madre de Dios Region holiday package cost?
Choose from any combination of hotels, flights and car rentals, and you can be holidaying in Madre de Dios Region from just . And the more you bundle, the more money you save. The getaway of your dreams has never been more affordable.
How do I get a cheap travel package to Madre de Dios Region?
Browse and book everything all in one place with our Madre de Dios Region holiday packages. We have incredible bargains on hotels, flights and more that'll keep your pocket happy and your sense of adventure alive. And, with more than 550 airlines and 1 000 000 properties throughout the world to pick from, you'll have endless opportunities to mix and match as you please.
What are the top hotels in Madre de Dios Region?
For properties in Tambopata with friendly service and cosy beds, you can't beat Kapievi Ecovillage and Inkaterra Reserva Amazonica. If you plan to explore Las Piedras as well, you'll get a solid night's sleep at Copasu Hotel or Tarantula Hostel.
How far in advance should I book my Madre de Dios Region holiday?
Reward yourself with the biggest variety and the lowest prices by booking your holiday to Madre de Dios Region nice and early. Airlines generally advertise flight tickets around 12 months prior to departure, so reserve your spot ASAP. Having said that, Expedia is constantly working to give you the best deals around, so it's never a bad time to book your dream holiday!
What does an Expedia Madre de Dios Region travel package include?
Hotels, flights and car rentals — we connect you to the very best bargains. All you have to do is decide on your favourite combination. After you've made your booking, you can add on the fun stuff like sightseeing activities. Our travel packages make it easy to create an awesome Madre de Dios Region getaway.
What should I know before booking a Madre de Dios Region travel package?
When you book your flights, hotels and car rentals together, you'll enjoy amazing discounts. Whether you're planning a mountain getaway in a cabin or want to stay in a cosy apartment in the city, Expedia will help make it happen.
Can I choose my airline with a Madre de Dios Region Expedia holiday package?
Yes — and it's easy too. Expedia has access to more than 550 partner airlines globally. Our packages give you the flexibility to pick from available flights, hotels and activities that suit you.
If I'm not able to travel, can I cancel my Madre de Dios Region holiday package?
It's difficult to predict what tomorrow might bring, so it's comforting to know that you can cancel or change your Madre de Dios Region holiday package. If you booked in the last 24 hours, you may be entitled to a refund. If your booking is older, your airline, hotel or car rental company may charge a fee. Check our Customer Service Portal to find out more.

Discover the most popular places to visit in Madre de Dios Region

Manu National Park

Explore the great outdoors at Manu National Park, a lovely green space in Manu.

Manu National Park

What to do in Madre de Dios Region

Puerto Maldonado: Kayak and Zip Line Adventure + Monkey Isla

Puerto Maldonado: Kayak and Zip Line Adventure + Monkey Isla

AU$90
per adult
Puerto Maldonado: Kayak and Zip Line Adventure + Monkey Isla
Puerto Maldonado: 4-Day Tambopata Rainforest Tour

Puerto Maldonado: 4-Day Tambopata Rainforest Tour

AU$585
per adult
Puerto Maldonado: 4-Day Tambopata Rainforest Tour
Picture 2 for Activity Puerto Maldonado : Trip to Yacumama Lake + sunset

Puerto Maldonado : Trip to Yacumama Lake + sunset

AU$62
per adult
Puerto Maldonado : Trip to Yacumama Lake + sunset
See all activities in Madre de Dios Region
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.